Andres Bendesky

@bendesky.bsky.social

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Neuroscience – behavior – genetics – evolution
Columbia University

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Andres Bendesky

@natanaels.bsky.social's work modeling how mutations accumulate with age and time, now out in PLoS Biology (joint with @marcdemanuel.bsky.social, William Milligan & Guy Sella): journals.plos.org/plosbiology/...

The clock-like accumulation of germline and somatic mutations can arise from the interplay of DNA damage and repairjournals.plos.org The rate at which DNA mutations accumulate varies substantially across cell types and tissues in the human body, but the origin of these differences is not well understood. This study develops a model...

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The Kautt Lab is looking for a research tech to join us at WashU in St. Louis! A great fit for anyone interested in genomics, speciation, and animal behavior. Includes wet lab, animal-, and fieldwork opportunities, all in a vibrant and affordable city wustl.wd1.myworkdayjobs.com/en-US/Extern...

Research Lab Technician II - Biologywustl.wd1.myworkdayjobs.com Scheduled Hours 37.5 Position Summary The Kautt Lab seeks a skilled Research Lab Technician. The lab employs an integrative approach, combining evolutionary genomics with molecular experiments, behavi...

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New paper alert: Towards an unbiased characterization of genetic polymorphism, from Weigel & Nordborg labs w/ help from many friends. TL;DR: Complete genomes pose tremendous analytical challenges, but reveal many fascinating facets of genome evolution. #plantscience www.biorxiv.org/content/10.1...

Interesting that "the best music" has the sharpest distribution at 10-20 years of age

Great Washington Post nostalgia study. Adults think U.S. society was historically nicest and comfiest—most moral and close-knit, families happiest—whenever they happened to be little kids, and culture (music, movies, TV, fashion, sports, food) best whenever they were adolescents. wapo.st/3WXd9xS

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New lab preprint! 🔥🔥 work by super postdoc Alison Philbrook. 🧪 C. elegans sensory neurons have gorgeous #cilia at their dendrite ends. We’ve always thought that a) no cilia = no sensory responses, & b) no IFT = no cilia. Punchline is we thought wrong. Read paper for more! #neuroscience

Differential modulation of sensory response dynamics by cilia structure and intraflagellar transport within and across chemosensory neurons https://www.biorxiv.org/content/10.1101/2024.05.16.594529v1

Differential modulation of sensory response dynamics by cilia structure and intraflagellar transport within and across chemosensory neurons https://www.biorxiv.org/content/10.1101/2024.05.16.594529v1 www.biorxiv.org Sensory neurons contain morphologically diverse primary cilia that are built by intraflagellar trans

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Andres Bendesky

great @washingtonpost.com article about this exciting discovery! wapo.st/44M3fRI

Excited to share our newest paper, in which we report our discovery that monogamous oldfield mice have very recently evolved a novel cell type in their adrenal glands that promotes parental care Work led by the fabulous Natalie Niepoth and @jennymerritt.bsky.social 🧵 rdcu.be/dH1Kn

Some mice have a cheating heart. It’s a hormonal thing, scientists find.wapo.st Oldfield mice are monogamous. The deer mouse prefers the swinging lifestyle when it comes to sexual partners.

A really nice News and Views about our paper by @tollkuhn.bsky.social 🙏🏽 www.nature.com/articles/d41...

Parental-care puzzle in mice solved by thinking outside the brainwww.nature.com Both parents of oldfield mice care for offspring, whereas in deer mice, mothers usually care for pups. The discovery of a type of adrenal-gland cell that is present in oldfield mice but not in deer mi...

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Thrilled to share a new lab pre-print from graduate student Tris Dodge! Tris & co elegantly uncover the genetic underpinnings and fitness consequences of a sexual mimicry polymorphism in Xiphophorus birchmanni: www.biorxiv.org/content/10.1...

Complex structural variation and behavioral interactions underpin a balanced sexual mimicry polymorphismwww.biorxiv.org bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

How do animals know when it’s their turn to communicate during a conversation? In our latest preprint, we study the behavior and neurobiology of aggressive visual turn-taking of Siamese fighting (betta) fish to find out. Work lead by Claire Everett 🧵 1/8 www.biorxiv.org/content/10.1...

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Andres Bendesky

I’m fed up with people pointing out all the mistakes in my poetry so I’ve written them this poem; it’s called ‘Pedant’s’.

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Andres Bendesky

Judith with the Head of Holofernes, by Charles Mellin, 1630, 📸 by Brian Babineau

Fun blog post on our recent paper on the genetics of gamecocks (doi.org/10.1093/g3jo... ) genestogenomes.org/scientists-p...

Scientists pinpoint the “fight” in fighting chickensgenestogenomes.org A genome-wide association study published in G3: Genes|Genomes|Genetics offers insights into the genetic origins of aggression in gamecocks.

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Andres Bendesky

Thinking about postdoctoral research? Think about it in New York, at the NYU Biology Emerging Scholars Symposium. Apply by April 21 for an all-expenses-paid trip to the city and a chance to talk about your science and your ideas for the future. as.nyu.edu/departments/...

Emerging Scholars Symposium 2024as.nyu.edu

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One of our current research assistants is heading to grad school and we are looking for a new person to start this summer/fall! Great position for research experience pre-grad school (genetics, evolution, mol biol) - please repost and send qs to schumer at stanford dot edu! shorturl.at/wELM6

Life Science Research Professional 1 in School of Humanities and Sciences, Stanford, California, United Statesshorturl.at Life Science Research Professional 1 The School of Humanities and Sciences (H&S) is the foundation of a liberal arts education at Stanford. The...

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Andres Bendesky

New paper out with Sarah Greer Rodock: "Spit For Science and The Limits of Applied Psychiatric Genetics" I think it is open access, though I had a hard time getting to it. muse.jhu.edu/pub/1/articl...

Project MUSE - Spit for Science and the Limits of Applied Psychiatric Geneticsmuse.jhu.edu

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Andres Bendesky

Really pleased to to see this study from our lab at LMU Munich in collaboration with the U. of Rosario, led by PhD students Matteo Rossi and Alexander Hausmann finally, finally out: Adaptive introgression of a visual preference gene www.science.org/doi/10.1126/...

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Andres Bendesky

For those in the NY area, SAVE THE DATE (& register) for a Symposium on Human Genetics at Columbia University: Oct 10-11 2024. Talks will also be streamed.

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Andres Bendesky

The use of the phrase “ancestry-specific variant” is increasing, particularly to describe rare Single-nucleotide variants (SNVs). But these alleles are not ancestry-specific. They have not yet been found elsewhere, but they will be. 1/n

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Andres Bendesky

I have been following the discussion around how best to represent and label human genetic variation, and thought it might also be worth discussing an aspect of the broader context. 1/n

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Andres Bendesky

Guest blog from me on Dynamic Ecology, a guide for beginning grads on developing a reading habit and project ideas! Super grateful for reposts :)

Non-definitive guides on developing a reading habit & generating project ideasdynamicecology.wordpress.com Note from Meghan: This is a guest post by my colleague Gina Baucom on a topic that's sure to be of interest to lots of readers! *** I lead a graduate-level professional development seminar* where we r...

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Andres Bendesky

50,000 years of Evolutionary History of India: Insights from ~2,700 Whole Genome Sequences https://www.biorxiv.org/content/10.1101/2024.02.15.580575v1

50,000 years of Evolutionary History of India: Insights from ~2,700 Whole Genome Sequences https://www.biorxiv.org/content/10.1101/2024.02.15.580575v1 www.biorxiv.org India has been underrepresented in whole genome sequencing studies. We generated 2,762 high coverage

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Over the🌙 to share our accepted article, lead by rockstar @Hagar_k_Soliman 👩‍🎤. We really had to stretch our plant-minded brains in this one- a very fun exploration into mammals, plants, and conflict! 🌺🐁Thanks for the opportunity, @theAGA_org! academic.oup.com/jhered/advan...

Come join us in the Zuckerman Institute at Columbia on May 17th for the 2024 New York Area Population Genetics Meeting. Keynotes by Lindy McBraide and Cedric Feschotte Register here zuckermaninstitute.columbia.edu/new-york-are...

NYAPG24zuckermaninstitute.columbia.edu Join us on Friday, May 17, 2024 for an all-day conference hosted at Columbia’s Zuckerman Institute showcasing research in evolutionary genetics. Alongside formal presentations, the conference will enc...

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Andres Bendesky

TMEM63B functions as a mammalian thirst receptor https://www.biorxiv.org/content/10.1101/2024.02.01.578339v1

TMEM63B functions as a mammalian thirst receptor https://www.biorxiv.org/content/10.1101/2024.02.01.578339v1 www.biorxiv.org Thirst drives animals to reinstate water homeostasis by fluid intake. An increase of blood osmolalit

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Andres Bendesky

I've written up a "crash course" on population genetics parameters useful for thinking about recent selection, heritability, and group differences (as part of a longer write-up on these concepts): gusevlab.org/projects/hsq... A short (ish) thread of key points: threadreaderapp.com/thread/17507...

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Andres Bendesky

Just in time for the holidays, Jeff Groh cracks the story of an ancient, balanced polymorphism for heterodichogamy (male vs female flower order) in walnuts & pecans www.biorxiv.org/content/10.1...

Distinct ancient structural polymorphisms control heterodichogamy in walnuts and hickorieswww.biorxiv.org bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

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Andres Bendesky

Excited to share a new pre-print from our lab that demonstrates surprisingly repeatable genome evolution in replicated Xiphophorus hybrid populations! Led by former postdoc Quinn Langdon with substantial contributions from Jeff Groh from @gcbias.bsky.social's lab: www.biorxiv.org/content/10.1...

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