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Pardon me as I scream into a pillow about the fact that Johnson & Johnson slashed Janssen's vaccine R&D and abandoned their adult RSV vaccine even though that protected older adults from severe RSV for *3 seasons* with a single dose: www.sciencedirect.co...
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You can use my screaming pillow! I use it whenever I think about how we had a Lyme Disease vaccine that was pulled from the market because of “low demand” 🙃🙃
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there is another one on the way from someone bigger and slightly less likely to give up
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From what I can tell from press releases it sounds like they felt like they would be too slow to get to market. Also I expect that the fact that it’s an adenovirus vector had a chilling effect after the cases of VITT/TTS came to light
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Ha, thanks. It was more Existential Despair Rhetoric than a real q — I didn’t know the details, but could guess. I think a lot of people don’t recognize that the vaccine distribution/coverage stuff is…bad now. A longer term is super helpful. (I had to pay cash for a std vax my doc prescribed. 🤬)
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I will never not be mad about that. I’m grateful I had the cash, because I needed it, but that my insurance company made it too hard to access in a timely fashion and the — I forget which agency I contacted — nice regulator said “yeah they can do that, have you considered lobbying?” infuriates me.
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Is there reason to think a different adenovirus would be safer? That issue really needs to be resolved before this tech is used again IMO.
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Since they know the principle of action (right?) they could at least eliminate that in vitro.
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It just seems like a very very rare but nearly 100% fatal side effect is not a reasonable tradeoff.
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But you still have to validate that it prevents the effect in vivo
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JJJ has the most fucked vibes of any large pharma organization, I do not understand them at all