Cornelius J

Profile banner

Cornelius J

@jcornelius.bsky.social

Not actually a lizard. Or am I?
Avatar
Avatar
www.cell.com/cell-stem-ce... "Our findings demonstrate that hPSC-derived DA neurons are susceptible to SARS-CoV-2, identify candidate neuroprotective drugs for COVID-19 patients, and suggest the need for careful, long-term monitoring of neurological problems in COVID-19 patients."
SARS-CoV-2 infection causes dopaminergic neuron senescencewww.cell.com Yang and colleagues demonstrate that SARS-CoV-2 can infect hPSC-derived midbrain dopamine (DA) neurons and induce cellular senescence. Several drug candidates were identified to rescue SARS-CoV-2 infe...
Avatar
Avatar
Avatar
youtu.be/2HGi81LsXtA?... "This video essay offers a useful primer to this syndrome that is already affecting tens (likely hundreds) of millions of people across the world. Please share this information with your community and advocate for authorities to start taking our health seriously..."
Why is EVERYONE more SICK?youtu.be *Why does everyone keep getting sick? Spring flu, summer flu, concert flu, colds, endless coughing, mysterious bugs, allergies - why do our immune systems suck now?? What's with all the new health issues like diabetes, high cholesterol and fatigue? Why are more athletes having heart attacks? Why do so many have brain fog, memory problems and can't think as well as before? Is our gut microbiome health worse? Are we all just more tired and ill than before for no reason?* Well, spoiler– it's not "lockdowns" or "immunity debt" or "thejab" or not exercising or not enough essential oils or vitamins or natural remedies or not thinking enough positive, high-vibration, wellness thoughts. It's something you may have never even heard of thanks to public health and governments not doing their jobs, but something you've probably already had a lot of encounters with, something you know ~deep down~ is not as over as the mainstream media or your profit-minded employer says it is, something that will not go away just because we wish it really hard.. This video essay offers a useful primer to this syndrome that is already affecting tens (likely hundreds) of millions of people across the world. Please share this information with your community and advocate for authorities to start taking our health seriously, because we all deserve so much better.. Subscribing, liking the video and commenting also helps out in satisfying the Youtube gods and getting this content to reach more people. If this is your first time hearing about it, your emotional impulse might be to say that it can't be real, that it must be an exaggeration or conspiracy. If that's the case, we assure you we have only used high-quality, credible, reputable sources and research, which we recommend checking out in the reference list below. The PDF has short summaries for all the studies included, to make it as easy to understand and accessible as possible, with some bonus resources for those of you who like deep diving into topics. 💕, 𝕷 & 𝕯 Reference list: https://www.dropbox.com/scl/fi/d4dzdprw7rrcdsii6xvlq/Lola-Germs-Reference-List-light-mode.pdf?rlkey=ufy6cp1kq7qd1b6ovhko938o1&st=oettjgvf&dl=0 Dark background version: https://www.dropbox.com/scl/fi/qxr3v7bu77ldtbvdkxwyr/Lola-Germs-Reference-List-dark-mode.pdf?rlkey=whw7etc86cyx5m2iv5tga0h3l&st=1dt7i13d&dl=0 💚 If you found this video useful and would like to chime in to help keep this project going, you can support by donating via Ko-fi (and get some perks too): 💚 Ko-fi: https://ko-fi.com/lolagerms (Patreon not currently active) !! Follow LolaGerms on: Instagram: https://www.instagram.com/lola.germs/ Tiktok: https://www.tiktok.com/@lolagerms !! More resources: Linktree: http://linktr.ee/lolagerms !! Check out more videos! Playlist on how masks work and how to fit test them to make sure they seal, different international names for respirators & more: https://youtube.com/playlist?list=PLPNcdxhQxkygKVw60upLb4LPzIWqfdKlM&si=-2dz92Wl9az-I8Xc More science explained videos: https://youtube.com/playlist?list=PLPNcdxhQxkyg2EDShXe7mvx9ZOz6gu__X&si=l5CTgTTuqBGAUNi- It's airborne: https://youtube.com/playlist?list=PLPNcdxhQxkyhgzUwvL3JEjt8H5i4qoR3u&si=1M7XtDJBEIQQfp5U !! Check out how you can get involved in your community: https://www.instagram.com/covidactionmap/ We are working on getting this video subtitled in multiple languages for broader accessibility. Image credits: https://www.dropbox.com/scl/fo/lm2ldlijehch1tfxc0fm5/h/Image%20Credits.pdf?rlkey=k2v3dwkim4uc2c2lb4fivfoqp&e=1&st=fturqdre&dl=0 Chapters: 00:00 - 00:54 Intro 00:54 - 02:05 What is long COVID? 02:05 - 05:04 What is LC, more specifically? 05:04 - 10:20 Some people are very ill (ME/CFS) 10:20 - 11:51 Who counts as having LC? 11:51 - 16:45 Why doesn't anyone I know have LC? 16:45 - 21:00 Why doesn't my doctor know about LC? 21:00 - 24:00 The vax and relax strategy is wrong 24:00 - 28:14 Being fine now ≠ fine forever 28:14 - 35:30 What the AIDS epidemic can teach us 35:30 - 41:39 Won't the government just fix it? 41:39 - 45:06 Canada is doing what to "fix it"?? 45:06 - 51:22 It doesn't have to be like this 51:22 - 54:54 Recap #immunity #health #wellness #medicine #vitamin #vitamins #medicine #medical #clinical #doctor #guthealth #insomnia #depression #anxiety #adhd #natural #naturalremedies #naturalremedy #diy #podcast #sick #fatigue #exercise #flu #cold #immunesytem #publichealth #videoessay #commentary #crashcourse #summerflu #springflu #allergies #mindset #positivity #education #educational #science #research #stomachbug #tired #tiredness #fatigue #brainfog #memory #ibs #diabetes #cholesterol #heartattack #cardiovascular #bloodclots #ms #multiplesclerosis #HIV #EBV #HPV #autoimmune #autoimmunity #autoimmunedisease #disease #illness #ill #sickness #disability #ableism #advocacy #activism
Avatar
journals.asm.org/doi/10.1128/... "Interestingly, several antihistamine drugs, including clemastine, astemizole, azelastine, brompheniramine, and ebastine, which have been approved for treating allergy symptoms without side effects for decades, have been found to prevent SARS-CoV-2 infection..."
The histamine receptor H1 acts as an alternative receptor for SARS-CoV-2 | mBiojournals.asm.org In addition to human angiotensin-converting enzyme 2, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can utilize alternative cofactors to facilitate viral entry. In this study, we discov...
Avatar
Avatar
Avatar
Avatar
Reposted byAvatar Cornelius J
Avatar
www.nature.com/articles/s41... "Cetylpyridinium chloride (CPC), a quaternary ammonium compound, which is present in mouthwash, is effective against bacteria, fungi, and enveloped viruses. SARS-CoV-2 can replicate in oral cavity and release into saliva."
Antiviral effect of cetylpyridinium chloride in mouthwash on SARS-CoV-2 - Scientific Reportswww.nature.com Scientific Reports - Antiviral effect of cetylpyridinium chloride in mouthwash on SARS-CoV-2
Avatar
www.nature.com/articles/s41... "Cetylpyridinium chloride (CPC), a quaternary ammonium compound, which is present in mouthwash, is effective against bacteria, fungi, and enveloped viruses. SARS-CoV-2 can replicate in oral cavity and release into saliva."
Antiviral effect of cetylpyridinium chloride in mouthwash on SARS-CoV-2 - Scientific Reportswww.nature.com Scientific Reports - Antiviral effect of cetylpyridinium chloride in mouthwash on SARS-CoV-2
Avatar
Avatar
"Neomycin prophylaxis affords antiviral protection against SARS-CoV-2 infection and disease."
Avatar
"These findings suggest that neomycin has the potential to be harnessed as a host-directed antiviral strategy for the prevention and treatment of respiratory viral infections."
Avatar
"In healthy humans, intranasal application of neomycin-containing Neosporin ointment was well tolerated and effective at inducing ISG expression in the nose in a subset of participants."
Avatar
"Prophylactic or therapeutic administration of neomycin provided significant protection against upper respiratory infection and lethal disease in a mouse model of COVID-19."
Avatar
"Repurposing generic medicine has the potential to bring new treatments for infectious diseases to patients efficiently and equitably."
Avatar
www.pnas.org/doi/10.1073/... "In this work, we repurpose a widely available generic medication, neomycin, as a host-directed antiviral strategy to combat upper respiratory viral infection and transmission, offering hope for addressing a significant global health challenge."
Intranasal neomycin evokes broad-spectrum antiviral immunity in the upper respiratory tract | PNASwww.pnas.org Respiratory virus infections in humans cause a broad-spectrum of diseases that result in substantial morbidity and mortality annually worldwide. To...
Avatar
"Studies in humans and animals suggest that mucosal immunity is more effective than systemic immunity in controlling replication of respiratory viruses."
Avatar
www.nih.gov/news-events/... "A Phase 1 trial testing the safety of an experimental nasal vaccine that may provide enhanced breadth of protection against emerging variants of SARS-CoV-2, the virus that causes COVID-19, is now enrolling healthy adults at three sites in the United States."
NIH-sponsored trial of nasal COVID-19 vaccine openswww.nih.gov Candidate vaccine could provide enhanced breadth of protection against emerging SARS-CoV-2 variants.
Avatar
Avatar
"The NIH said MPV has an affinity for epithelial cells that line the respiratory tract and may be useful for delivering the vaccine to body sites where natural coronavirus infection begins."
Avatar
"The investigational vaccine, called MPV/S-2P, uses a murine pneumonia vector (MPV) to deliver a version of the SARS-CoV-2 spike protein.
Avatar
www.cidrap.umn.edu/covid-19/nih... "With the continual emergence of new virus variants, there is a critical need to develop next-generation COVID-19 vaccines, including nasal vaccines, that could reduce SARS-CoV-2 infections and transmission."
NIH announces launch of clinical trial for nasal COVID vaccinewww.cidrap.umn.edu Nasal vaccines have the potential for reducing transmission and preventing milder illness.
Avatar
"Long COVID appears to be a chronic condition with few patients achieving full remission," according to a new Academy of Sciences report. The report concludes that long COVID recovery can plateau at 6-12 months.
Avatar
www.medscape.com/viewarticle/... "People who have recovered from long COVID can suffer relapses or flare-ups from new viral infections — not just from COVID but from cold, flu, and other viral pathogens, researchers have found."
Cold, Flu Virus Can Trigger Long COVID Relapseswww.medscape.com Those who treat and research long COVID warn that viral persistence and reactivation are real risks for some patients.
Avatar
The most common causes include: -Protein-energy undernutrition -HIV infection -COVID-19:🙈🙊🙉🟰🤑🤐🤥 -Certain other viral infections Protein-energy undernutrition is the most common cause worldwide.
Avatar
Lymphocytopenia - Hematology and Oncology - Merck Manual Professional Edition www.merckmanuals.com/professional... Lymphocytopenia can be: -Acquired -Inherited Acquired lymphocytopenia- -Acquired lymphocytopenia can occur with a number of other disorders.
Lymphocytopenia - Lymphocytopenia - Merck Manual Professional Editionwww.merckmanuals.com Lymphocytopenia - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version.
Avatar