Maite Colinas
🌱-scientist at MPI for Chemical Ecology. Digging 🌱, natural products, enzymes, regulation, evolution, not necessarily in this order. Former MSCA fellow. Daydreamer.(she/her)
Cell-type aware regulatory landscapes governing monoterpene indole alkaloid biosynthesis in the medicinal plant Catharanthus roseuswww.biorxiv.org bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
Single-cell proteomics differentiates Arabidopsis root cell types https://www.biorxiv.org/content/10.1101/2024.04.09.588771v1 www.biorxiv.org Recently, major advances have enabled the exploration of cellular heterogeneity using single-cell pr
Biosynthesis of the allelopathic alkaloid gramine in barley by a cryptic oxidative rearrangementdoi.org The elusive gene required for the production of the defensive alkaloid gramine in barley hs been discovered.
scGPT: toward building a foundation model for single-cell multi-omics using generative AI - Nature Methodswww.nature.com Pretrained using over 33 million single-cell RNA-sequencing profiles, scGPT is a foundation model facilitating a broad spectrum of downstream single-cell analysis tasks by transfer learning.
An oxidative photocyclization approach to the synthesis of Securiflustra securifrons alkaloidswww.science.org Sequential photocyclization reactions enable the synthesis of three skeletally distinct classes of marine alkaloids.
Phylochemical mapping of natural products onto the plant tree of life using text mining and large language models. https://www.biorxiv.org/content/10.1101/2024.02.16.580694v1 www.biorxiv.org Plants produce a staggering array of chemicals that are the basis for organismal function and divers
New Genomic Techniques: MEPs back rules to support green transition of farmers | News | European Par...www.europarl.europa.eu For a more sustainable and resilient food system, MEPs support a simpler process for NGT plants equivalent to conventional plants, while others must follow stricter rules.
Single-Cell RNA-seq based elucidation of the antidepressant hyperforin biosynthesis de novo in St. John's wort. https://www.biorxiv.org/content/10.1101/2024.01.24.577018v1 www.biorxiv.org Hyperforin is the compound responsible for the effectiveness of St. John's wort (Hypericum perforatu
Complete biosynthesis of the potent vaccine adjuvant QS-21 - Nature Chemical Biologywww.nature.com Vaccine immunoadjuvants are central to vaccine efficiency. Now, the complete characterization of the biosynthetic pathway of QS-21, a potent immunoadjuvant produced by the Chilean soapbark tree, has b...
CasPEDIA: A Functional Classification of Cas Enzymesblog.addgene.org A review of the CasPEDIA resource and its features.
Natural Product Weirdness Returnswww.science.org
edgeR 4.0: powerful differential analysis of sequencing data with expanded functionality and improved support for small counts and larger datasets https://www.biorxiv.org/content/10.1101/2024.01.21.576131v1 www.biorxiv.org edgeR is an R/Bioconductor software package for differential analyses of sequencing data in the form
Best practices for the execution, analysis, and data storage of plant single-cell/nucleus transcript...academic.oup.com Abstract. Single-cell and single-nucleus RNA-sequencing (scRNA-seq and snRNA-seq) technologies capture the expression of plant genes at an unprecedented resolut