This, right here, is the #1 concern with Biden. You do not get to "flag" at night as POTUS. Any nervous Trump voter who *might* consider voting for Biden now is faced with a sundowning president. wapo.st/4cmS8Sg
Plenty of presidents have been incapacitated at various times for various reasons. Reagan had Alzheimer's for example.
Every time the vice-president steps in. This is not a problem.