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Oh my god, this is fucking huge. It was huge when we developed a daily PrEP pill that could prevent you from catching HIV; this is a successful phase III trial of a PrEP shot that will only need to be given *twice a year*. Still needs a confirmatory Phase III, but holy fuck.
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Good Lord, if it works as it seems to this could mean the end of HIV/AIDS in a decade or two. These researchers deserve a Nobel prize, or whatever medical researchers get.